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This lecture explores the origin of radionuclides in the lithosphere, hydrosphere, and atmosphere, which are remnants from supernova explosions. Topics include nuclear astrophysics, cosmic element formation, stellar energy production, and the evolution of the Milky Way. The lecture delves into the Big Bang, nucleosynthesis processes, and the evolution of stars, explaining the formation of elements and the abundance of isotopes. It also covers the evolution of the Earth, the role of radionuclides in the environment, and the impact of cosmic radiation. The presentation concludes with a discussion on the atomic abundances in the solar system and the significance of radionuclides in nature.