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This lecture delves into the practical applications of DNA replication, focusing on techniques like PCR and their versatile use in everyday life, such as in COVID testing and forensic sciences. The discussion also covers the importance of DNA fidelity, the challenges faced by cells when copying repetitive sequences, and the concept of microsatellites. The lecture further explores the distinction between mutations and polymorphisms, the significance of short tandem repeats in forensic analysis, and the process of DNA quantification using capillary electrophoresis. The instructor emphasizes the non-invasive nature of DNA analysis and the ethical considerations surrounding genetic profiling for personal traits.