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This lecture explores new advances in functional Magnetic Resonance Imaging (fMRI) in rodents, focusing on the transition from network psychology to network physiology. Dr. Valerio Zerbi discusses the Center for Neuroprosthetics' research on the brain's connectivity and the impact of activating the Locus Coeruleus/Norepinephrine system. The presentation covers the infrastructure, core members, and core activities of the Center for Biomedical Imaging. It delves into the study design involving chemogenetics and optogenetics, as well as the implications of activating the Locus Coeruleus on brain network dynamics. The lecture concludes with insights into awake fMRI in rodents and the potential of rodent fMRI in understanding brain networks and their physiological drivers.