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This lecture discusses the development of an instrumented prosthesis aimed at improving implant positioning precision and patient outcomes. The project involved collaboration with an industrial partner and focused on integrating sensor data for doctors, providing quantitative and qualitative benefits. The lecture covers the engineering aspects, team collaboration, and the successful achievement of internal insights into the knee. The project also included a mechanical simulator to validate smart processes before implementing them in human subjects, with a focus on force and kinematic sensors for testing implant durability and prefatigue. The lecture concludes with insights into the potential benefits of the project for future prosthesis design and improvement.