Antigen Presentation: MHC Antigen Processing

This lecture covers the maturation of antigens within a cell, their interaction with MHC molecules, and the three antigen presentation pathways: endogenous, exogenous, and cross-presentation. It explains the biosynthesis of MHC class 1 and class 2 molecules, the processing of viral proteins, and the mechanisms of antigen presentation to TCD8 and TCD4 cells. The lecture also details the role of cross-presentation by dendritic cells in activating TCD8 responses against viruses. It concludes by summarizing the different antigen presentation contexts by dendritic cells, macrophages, and other cells to initiate T cell responses.