Lecture

Drug Targets: Receptors, Enzymes, and Transporters

Description

This lecture covers the classification of drug targets into receptors, enzymes, and transporters, with a focus on the top 10 drug indications such as antihypertensive, antineoplastic, and anti-inflammatory agents. It discusses the different types of receptors, including G-protein-coupled receptors and enzyme targets like cyclo-oxygenase and tyrosine kinases. The lecture also explores ion channels, transporter proteins, protein therapeutics, and gene therapy applications in drug targeting. The mechanisms of receptor-mediated activation of G proteins, GPCR signaling pathways, desensitization, and G protein-independent signaling are explained. Additionally, it delves into the physiological effects of adrenergic receptors, neurotransmitters in the peripheral nervous system, and drugs acting on noradrenergic nerve terminals.

About this result
This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.