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This lecture covers methanogenesis, the process by which organisms produce methane, focusing on the three types: hydrogenotrophic, methylotrophic, and acetoclastic methanogenesis. It also discusses the coenzymes involved in methanogenesis, such as Methanofuran, Methanopterin, Coenzyme M, Coenzyme F430, Coenzyme F420, and Coenzyme B. Additionally, it explores the specific biochemical pathways and the organisms involved, like Methanococcus, a thermophilic species that uses CO2 and H2 as energy sources but cannot fix N2, with some strains growing at extreme temperatures and pressures.