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This lecture covers case studies on needs assessments for Implementation Research (IR), focusing on different settings with unique challenges. It explores the potential for Community-Directed Interventions (CDI) in various contexts, emphasizing the importance of data-driven decision-making and community involvement. The lecture also discusses increasing coverage of interventions like IPT for malaria in pregnancy through innovative strategies such as mHealth reminders. Additionally, it addresses the role of Community Health Workers (CHWs) in handling drugs and using Rapid Diagnostic Tests (RDTs), highlighting the need for policy changes and program adaptations. Concluding with key messages, the lecture emphasizes the significance of tailored IR approaches to address service delivery challenges effectively.