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Lecture# Limit Cycles in Biological Systems

Description

This lecture covers the concept of limit cycles in biological systems, focusing on the existence and stability of these cycles. The instructor explains the conditions for the existence of limit cycles and analyzes the behavior of systems near these cycles. The lecture delves into the mathematical models used to describe limit cycles and provides examples of biological systems exhibiting limit cycle behavior, such as glycolysis oscillations. Various types of bifurcations and stability analyses are discussed, highlighting the importance of limit cycles in understanding the dynamics of biological systems.

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In course

Instructors (2)

BIO-341: Dynamical systems in biology

Life is non-linear. This course introduces dynamical systems as a technique for modelling simple biological processes. The emphasis is on the qualitative and numerical analysis of non-linear dynamical

Related concepts (100)

Period-doubling bifurcation

In dynamical systems theory, a period-doubling bifurcation occurs when a slight change in a system's parameters causes a new periodic trajectory to emerge from an existing periodic trajectory—the new one having double the period of the original. With the doubled period, it takes twice as long (or, in a discrete dynamical system, twice as many iterations) for the numerical values visited by the system to repeat themselves. A period-halving bifurcation occurs when a system switches to a new behavior with half the period of the original system.

Mathematical model

A mathematical model is an abstract description of a concrete system using mathematical concepts and language. The process of developing a mathematical model is termed mathematical modeling. Mathematical models are used in applied mathematics and in the natural sciences (such as physics, biology, earth science, chemistry) and engineering disciplines (such as computer science, electrical engineering), as well as in non-physical systems such as the social sciences (such as economics, psychology, sociology, political science).

Pitchfork bifurcation

In bifurcation theory, a field within mathematics, a pitchfork bifurcation is a particular type of local bifurcation where the system transitions from one fixed point to three fixed points. Pitchfork bifurcations, like Hopf bifurcations, have two types – supercritical and subcritical. In continuous dynamical systems described by ODEs—i.e. flows—pitchfork bifurcations occur generically in systems with symmetry. The normal form of the supercritical pitchfork bifurcation is For , there is one stable equilibrium at .

Lyapunov stability

Various types of stability may be discussed for the solutions of differential equations or difference equations describing dynamical systems. The most important type is that concerning the stability of solutions near to a point of equilibrium. This may be discussed by the theory of Aleksandr Lyapunov. In simple terms, if the solutions that start out near an equilibrium point stay near forever, then is Lyapunov stable. More strongly, if is Lyapunov stable and all solutions that start out near converge to , then is said to be asymptotically stable (see asymptotic analysis).

Limit set

In mathematics, especially in the study of dynamical systems, a limit set is the state a dynamical system reaches after an infinite amount of time has passed, by either going forward or backwards in time. Limit sets are important because they can be used to understand the long term behavior of a dynamical system. A system that has reached its limiting set is said to be at equilibrium.

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