This lecture covers the topic of self-diffusion in metals, focusing on face-centered cubic and hexagonal compact structures. It discusses the influence of temperature and pressure on diffusion, empirical correlations, and the comparison between self-diffusion and heterodiffusion. The lecture also explores diffusion mechanisms in solids, the diffusion coefficient, and the use of tracers to measure diffusion. Various defects in crystals, such as Schottky and Frenkel defects, are explained, along with the impact of temperature on diffusion. The presentation delves into specific dissemination mechanisms, the role of impurities, and the effects of pressure on diffusion.