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This lecture covers the transmission spectrum of molecular wires, focusing on the broadening effect in the presence of a hole. It discusses the analysis of isolated DTB, connection to gold electrodes, and the impact of different anchoring groups. The lecture also explores the influence of length, torsion, and type of anchoring group on the energy distribution. The instructor explains the charging effect, resonance, and the role of gates in controlling the current flow. Additionally, the lecture delves into the capacitive model of quantum dots, logic computation using molecular transistors, and the evaluation of transmission spectra.