Synchrotrons and X-ray Techniques

This lecture covers the rotation method in single-crystal diffraction, emphasizing the importance of capturing Bragg peaks passing through the Ewald sphere. It also discusses serial crystallography techniques, such as SFX at XFELs and SSX at synchrotrons, highlighting the benefits of high frame rates and the ability to investigate micron-sized crystals. The lecture delves into the applications of serial crystallography in studying atomic vibrations, molecular dynamics, and large-scale conformational changes in proteins. Additionally, it explores the use of pole figures to observe physical phenomena through structural changes induced by temperature, pressure, and magnetic fields.