Understanding Parkinson's Disease

This lecture provides an in-depth exploration of Parkinson's disease, from its historical clinical descriptions by James Parkinson to the current understanding of its genetic and molecular causes. It covers the challenges in diagnosing PD, the importance of non-motor symptoms, available treatments like dopamine replacement therapy and deep brain stimulation, and the neuropathological changes in the brain. The lecture also delves into the role of the basal ganglia in motor control, the impact of dopamine loss, and the various pathways involved in PD. Additionally, it discusses the significance of early diagnosis, disease progression, and the socio-economic burden associated with PD.