Inhibitor Design & Analyses

In course

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Description

This lecture covers the principles of inhibitor design and analysis, focusing on identifying compounds that can form covalent bonds and those that cannot. Topics include functional groups for covalent bond formation, nucleophilic amino acids, and specific inhibitors for various diseases. The session also delves into experimental design considerations for drug development, such as deconvoluting reversible components of covalent drugs and determining assay readouts.

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