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This lecture covers hardware technologies and applications, focusing on the quantum stack, fidelity to electronic circuit specifications, cryogenic electronics, quantum sensing, interfacing qubits with classical processors, quantum computing stack, cryo-CMOS modeling, cryo-CMOS parameters, mobility over temperature, and modern processes. It delves into choosing technologies like single-electron transistors and superconducting devices, discussing cryo-CMOS characterization, transistor mismatch, low-noise amplifiers, quantum-classical interface, amplifier classification, performance, impedance matching, coaxial cables, and ADC examples. The lecture also explores sampling, quantization, signal-to-noise ratio, effective number of bits, quantization noise, ADC limitations, INL, DNL, ADC architectures, and more.