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This lecture explores the field of supramolecular chemistry, focusing on molecular machines and motors. Topics include the design principles for Brownian molecular machines, the operation of molecular switches and motors, and the development of photochemically driven molecular pumps. The instructor discusses the concept of molecular-level devices and machines, highlighting the controlled motion in mechanically interlocked architectures. The lecture delves into the synthesis and functioning of molecular shuttles, as well as the experimental support for rotary motion in natural and artificial molecular systems.