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This lecture covers the process of spermatogenesis in the seminiferous tubules and the pathway followed by spermatozoa from the tubule straight to the spongy urethra. It also includes a review of the histological structure of male genital organs, referencing specific chapters for further study. The presentation delves into the historical understanding of embryology, from ancient theories to modern scientific knowledge, detailing the development of the embryo from fertilization to birth. Additionally, it explores the microanatomy of the testis, epididymis, and other male reproductive structures. The lecture concludes with a focus on the rete testis, describing its intricate network of canaliculi and its role in the testicular mediastinum.