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This lecture covers the concepts of chemical equilibria and reactivity, focusing on the autoprotolysis of water, weak acid dissociation, buffer solutions, titration curves, and the use of indicators. It also explains the Henderson-Hasselbalch equation, the distribution diagram of weak acids, and the titration of strong and weak acids. The lecture emphasizes the importance of buffer solutions in maintaining constant pH during reactions and explores the practical applications of acid-base titrations.