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This lecture covers the concept of Closed-Loop Lifecycle Management for Sustainable Development, focusing on Circular Economy principles and Zero Defect Manufacturing strategies. It discusses the transition from a Linear Economy to a Circular Economy, emphasizing the importance of minimizing waste and maximizing resource efficiency. The lecture explores the implementation of Closed-Loop Lifecycle Management in technical spheres, addressing issues such as degradation, failure, defects, and solutions like Zero Defect Manufacturing. It also delves into topics like predictive maintenance, Big Data Analytics, and the role of IoT and PEID in manufacturing processes. The lecture highlights the significance of data sharing, ontologies, and cognitive twins in optimizing manufacturing processes and ensuring sustainable development.