This lecture provides an overview of the Nanotera program, which focuses on using nanotechnologies to address large-scale problems in health, environment, and energy. The program has funded numerous projects involving interdisciplinary collaboration among engineers, medical doctors, and scientists from various universities in Switzerland. The lecture highlights key features, such as the involvement of over 15 institutions and the work of around 300 PhD students. It also discusses the evolution of the program, the distribution of activities across different themes, and the importance of technology transfer through PhD students. The instructor emphasizes the need for closer interaction between academia and industry, advocating for a funding scheme that bridges the gap between research and innovation.