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This lecture explores the fascinating world of poisonous frogs, focusing on their unique ability to synthesize toxic alkaloids from their diet of ants, mites, and termites. The most potent alkaloid, batrachotoxin, found in the golden poison frog, can kill multiple humans. The lecture also delves into the chemistry of alkynes, hydrocarbons with triple carbon-carbon bonds, discussing their nomenclature, importance, and reactions. Additionally, it covers the synthesis and applications of alkynes in medicinal compounds, emphasizing their role as antibacterial, antifungal, and antiparasitic agents.