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This lecture covers how to call functions, pass parameters, and handle global variables in programming. The instructor demonstrates the importance of correctly passing parameters to functions, the scope of sub-functions, and the risks associated with global variables. Additionally, the lecture explores the concept of debugging tools, such as breakpoints and interactive variable modification, to troubleshoot code effectively. The use of vectorization in programming is also discussed, emphasizing its efficiency in processing large datasets. Practical examples and performance comparisons highlight the benefits of vectorization in improving code execution speed.