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This lecture explores the mechanics of wrinkled structures, focusing on the behavior of nano- and micro-structures, sustainable manufacturing in architecture, and phase separation. It delves into topics such as compression of thin sheets on different substrates, wrinkling of growing thin films, and the critical swelling strain of thin sheets. The lecture also covers the wrinkling of stiff films on soft substrates, the tuning of wetting angle via wrinkling, and the formation of DNA nanowires. Additionally, it discusses the interaction of wrinkled surfaces with external forces, the folding of wrinkled skin due to capillary forces, and the growth of bacterial biofilms on agar substrates.