This lecture covers the foundational concepts of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI), including nuclear spin dynamics, pulse sequences, and image reconstruction. It delves into the interactions between magnetic fields and matter, the manipulation of spins using RF pulses, and the principles behind image acquisition and quality control. The instructor explains the significance of gyromagnetic ratios, Larmor frequencies, and the role of different pulse sequences in generating MR images. Additionally, the lecture explores the safety considerations of MRI, the interpretation of image artefacts, and the process of volume-based normalization for brain imaging.