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This lecture covers the design of biodegradable polymer materials, discussing factors affecting biodegradability such as chemical bonding, microstructure, crystallinity, and more. It delves into the macromolecular nature of polymers, explaining bonding types, segment structures, and domain regions. The instructor explores different bonding types like ester bonds and peptide bonds, highlighting their significance in polymer design. Additionally, the lecture touches on domain structures in polymers, erosion processes, and the sustainable approaches in the bioplastic industry. It also addresses the commercialization and innovative applications of polymers, emphasizing EPFL's potential leadership in the field.