NeuroRestore: Advancements in Neuromodulation Therapies for Walking Recovery

This lecture discusses the innovative approaches in neuromodulation therapies aimed at restoring walking abilities in individuals with spinal cord injuries. The instructor begins by highlighting the complexities of the mammalian walking system and the evolutionary significance of bipedal locomotion. The lecture details the mechanisms of spinal cord stimulation, emphasizing the importance of targeting specific neural pathways to reactivate movement. The concept of biomimetic stimulation is introduced, showcasing how electrical stimulation can mimic natural brain signals to facilitate walking. The instructor presents case studies demonstrating the effectiveness of these therapies in both animal models and human patients, including the use of digital bridges to connect brain signals with spinal cord stimulation. The lecture also explores the implications of these therapies for treating other neurological disorders, such as Parkinson's disease, and discusses the ongoing research aimed at enhancing the precision and efficacy of neuromodulation techniques. Overall, the lecture provides a comprehensive overview of the current state and future directions of neuromodulation therapies in rehabilitation.