This lecture series, led by the instructor from EPFL, focuses on the challenges faced by cities in managing urban infrastructures, such as transportation and water systems, energy, and pollution. Divided into four blocks, the course covers the introduction to urban infrastructures, the foundations of managing urban infrastructure systems, and in-depth discussions on energy and transport infrastructures. The first block introduces the urban infrastructure systems and the associated challenges, with sessions covering general introductions, system workings, dimensions, practical perspectives, and analytical viewpoints.