This lecture discusses the integration of machine learning with multiscale characterization to predict the mechanical properties of carbon nanotubes and their composites. The instructor introduces the Integrated Computational Materials Engineering (ICME) paradigm, which combines experimental observations and computational modeling across various scales to enhance material development. The lecture covers the significance of carbon nanotubes in engineering applications, particularly in civil engineering, and their role in improving material properties. The instructor explains the challenges of characterizing carbon nanotubes, including their tendency to form bundles, and how machine learning can assist in analyzing these complexities. The presentation highlights the use of advanced imaging techniques, such as laser scanning confocal microscopy and transmission electron microscopy, to gather detailed data on carbon nanotube structures. The instructor also emphasizes the importance of machine learning in predicting mechanical properties, showcasing how it can optimize material design and performance. The lecture concludes with insights on the future of material modeling and the potential of machine learning in enhancing the understanding of complex materials.