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This lecture covers the history, advantages, and classification of adhesives, including synthetic and sustainable options like natural adhesives and bioadhesives. It explores examples such as Velcro, gecko-inspired adhesives, and mussel-inspired bioadhesives. The discussion delves into the properties and applications of natural adhesives made from organic sources, as well as the interfacial interactions and cohesive mechanisms of mussel adhesives. Additionally, it examines the development of sustainable adhesives from marine organisms and biofilms, highlighting the use of genetically engineered materials for advanced applications in various industries.