This lecture covers the factors contributing to polymer aging and degradation, historical background of polymer industry, gas permeability in polymers, diffusion in polymers, and the thermo-oxidative degradation of polymers. It also discusses the stabilization against pyrolysis, adiabatic degradation, oxidation mechanisms, and the coupling between oxidative degradation and stress. The instructor explains the degradation of polymers during melt processing, the gas permeability in polymers, and the general reaction scheme of polymer oxidation. Additionally, it explores the stabilization against oxidation, polymer-based diffusion barrier materials, multilayer systems, and display technologies past, present, and future.