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This lecture covers the fundamental concepts of metabolism, including enzymes, energy metabolism, and ATP production. It explores the catalytic strategies of enzymes, the biosynthesis of molecules using cellular energy, and the major carriers involved in metabolic reactions. The discussion also delves into the energy production by oxidation, the role of ATP as a universal energy currency, and the formation of ATP using ionic gradients. Additionally, it examines the activation of carriers in metabolism, such as ATP, NADH, FADH, and Coenzyme A. The lecture concludes with a focus on the biochemical reactions of metabolism, emphasizing the importance of specific pathways and the different types of metabolisms.