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This lecture covers the evolution of vision systems in vertebrates, from the three-layered proto-retina to the duplex retina found in humans and other vertebrates. It explores the different types of retinal ganglion cells and their central projections, including the regulation of circadian rhythms and the pupillary light reflex. The lecture also delves into the organization of the visual thalamus (LGN) and the primary visual cortex (V1), detailing how visual information is processed and transmitted through the optic nerve. Additionally, it discusses the visuotopic organization of V1 and the cortical layers involved in visual processing.