This lecture covers the Ethereum Virtual Machine (EVM) bytecode instructions for simple loops and gas computation in Ethereum smart contracts. It explains the concept of gas, its role in protecting against DoS attacks, incentivizing miners, and the gas computation rules for different EVM instructions. The instructor demonstrates examples using the Remix Ethereum IDE, Metamask wallet, and Etherscan block explorer. Students learn about gas costs, gas budgets, and how miners are rewarded based on gas consumption. The lecture also introduces special cases in gas computation, such as SSTORE rules. Overall, the lecture provides insights into the financial applications of blockchains and distributed ledgers.