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This lecture covers the mechanical properties of neural tissues, including the brain, spinal cord, and peripheral nervous system, focusing on their viscoelastic nature and structural variations. It also discusses the electrical properties of neurons, such as the resting potential and ion concentrations, as well as the recording of neural signals using techniques like EEG and ECoG. The presentation delves into the building blocks of neurons, the role of membranes in generating resting potentials, and the factors influencing membrane potential. Additionally, it explores the use of microelectrodes to measure membrane potential and the concept of Nernst potential for different ions.