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This lecture by the instructor covers the development of jet injection technology for skin delivery, focusing on the controlled thermocavitation process, laser-induced jets, and the mechanics of fluid-skin interaction. It explores the challenges and opportunities for small volume delivery into the skin, aiming to replace needles with fast-traveling liquid jets. The presentation delves into the energy balance, viscoelastic droplets, and the influence of additives on jet characteristics. The lecture also discusses the applications of this technology in medical pigmenting, drug delivery, and diagnostics, emphasizing the potential for portable platform development and the importance of process intensification.