Lecture
This lecture covers the chromosomal sex determination mechanisms in mammals, insects, birds, and some other species, exploring the impact of X and Y chromosomes on sex determination. It delves into dosage compensation strategies, such as X chromosome inactivation in mammals and other mechanisms in different organisms. The lecture also discusses the consequences of aneuploidy and the role of X-linked genes in human heredity, including examples of traits influenced by sex chromosomes. Additionally, it explains the concept of X chromosome inactivation, its molecular mechanisms, and its implications for gene expression and phenotypic variability.