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This lecture covers the practical aspects of implementation research, focusing on the strategies and results obtained in the field. Topics include randomized cluster trials, challenges in building trust, effectiveness evaluation, and scaling-up strategies. The instructor discusses key outcomes such as acceptability, adoption, feasibility, fidelity, coverage, and cost-effectiveness. Various evaluation methods like focus groups, interviews, and surveys are explored. The lecture also delves into the evaluation of efficacy and implementation results, showcasing real-world examples from a dengue vector control study in Colombia. Additionally, the importance of intersectoral collaboration, community mobilization, and scaling-up frameworks is emphasized, providing insights into successful scaling strategies and barriers faced in the process.