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This lecture introduces the importance of organometallic chemistry in various fields such as organic synthesis, catalysis, and medicine. It covers the types of ligands in organometallic complexes, the bonding in ligands, and the reactivity of unsaturated organic compounds when coordinated to transition metals. The lecture also discusses the preparation and structure of organometallic complexes, as well as their role in modifying classic organic reactivity. Examples of organometallic compounds, their interesting properties, and their applications as catalysts and in drug design are presented.