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This lecture explores the molecular mechanisms behind synaptic transmission, focusing on the process of synapse formation and neurotransmitter release. It delves into the steps of endo- and exocytosis, the role of synapses in learning and memory, and the computational aspects of cell biology. The lecture also discusses the challenges neurons face in maintaining membrane integrity and preventing excessive growth. Various computational models are presented to understand how synapses transduce electrical signals and the factors influencing pore formation in lipid membranes.