Immunoediting of Tumors: Experimental Evidence and Mechanisms

This lecture delves into the immunoediting hypothesis, discussing experimental evidence of tumor immunoediting in immunocompetent and immunodeficient mice. It explores the roles of the immune system in cancer, focusing on the mechanisms of tumor escape from immune pressure, such as antigen loss and immunosuppressive factors. The presentation also covers the use of flow cytometry in depth to study immune responses and tumor microenvironment factors like hypoxia. Additionally, it provides insights into cancer immunotherapy, its history, current status, and recent drug approvals, emphasizing the importance of antitumor immunity generation and regulation.