Neuron Types: Classification and Morphological Diversity

This lecture explores neuron types and their classification based on morphological diversity, emphasizing the importance of understanding the brain through dimensionality reduction and communication among scientists. Challenges in defining cell types and faithfully reconstructing morphologies are discussed, along with the impact of systematic artifacts on reconstruction accuracy. Various staining techniques and common antibodies used in immunostaining are presented, highlighting the complexities of neuron morphology. The lecture also covers the reconstruction process, including manual curation and automatic correction of artifacts, as well as the most common morphology formats. The summary emphasizes the ongoing complexity revealed by research and the need for better data organization and analysis tools.