Electron Transport Chain: Underlying Chemistry and Biology

This lecture covers the Electron Transport Chain (ETC) and Oxidative Phosphorylation (OXPHOS) processes, focusing on the chemistry and biology behind them. It explains the role of different complexes, such as NADH dehydrogenase, cytochrome C reductase, and cytochrome C oxidase, in transferring electrons and protons to generate energy. The lecture also delves into the functions of key molecules like coenzyme Q and cytochromes, detailing their involvement in electron transfer. Additionally, it discusses the redox potentials and free energy changes along the ETC, emphasizing the importance of oxygen as the final electron acceptor. The presentation concludes with insights into the proton pumping mechanisms and the overall significance of ETC in cellular energy production.