This lecture introduces the field of flexible bioelectronics, covering topics such as electronic devices, course organization, TA sessions, group projects, and course assessment. It explores the challenges of selecting materials, manufacturing methods, and designing flexible bioelectronic devices. The lecture delves into examples like foldable displays, brain electrodes, and biostamps, highlighting the interdisciplinary nature of the domain. It discusses the convergence of Biology, Materials Science, and Engineering in flexible electronics, emphasizing the need for new protective packaging and manufacturing methods. The lecture also addresses the adaptation of technology in medical devices and the objectives of the course, focusing on key concepts, materials, technologies, devices, and applications.