Paper-based Sensors: Development and Applications

This lecture explores the development and applications of paper-based sensors for diagnostic purposes, focusing on the detection of viral infections. It covers the historical evolution of paper-based sensors, from colorimetric detection in the 17th century to modern advancements using microfluidic technology. The lecture delves into the use of nanoparticles to enhance sensor sensitivity and the importance of reagent storage in paper diagnostics. It also discusses the integration of bioreactions for virus detection, including synthetic gene networks and mRNA sensors. The lecture highlights the design of reaction chambers in paper devices and the development of specific sensors for viruses like Ebola and Zika. Overall, the lecture emphasizes the potential of paper-based sensors in providing cost-effective, portable, and rapid diagnostic solutions.