Tissue-level Wave Patterns: Cellular Oscillators and Genetic Waves

This lecture discusses tissue-level wave patterns generated by cellular oscillators and genetic waves. It covers the segmentation clock as a rhythmic pattern generator, wave patterns arising from cellular oscillators, and the slowing of oscillators before arrest. The lecture also explores gene expression wave patterns, spatial frequency profiles, and the role of signaling gradients in positional information. Additionally, it presents a model for the single-cell pacemaker circuit and the generation of wave patterns at the single-cell level. The exercises focus on observing traveling waves at the tissue level and relating a simple model to the segmentation clock.