Chromatographic Models: Theory and Applications

This lecture covers chromatographic models, discussing the thermodynamic and kinetic parameters associated with the equilibrium distribution of solutes between stationary and mobile phases. Various models are presented, such as the Gaussian model for ideal systems, the Craig model for strongly retained solutes, and the binomial distribution model for solute separation units. The lecture also explores the characteristics of distribution functions, including the average advancement distance and the height equivalent to a theoretical plateau. Additionally, it delves into the convergence of binomial distributions to Poisson and normal distributions, providing insights into chromatographic signals and mass distributions in planar and elution chromatography.