This lecture explores the concept of dispositionalism in relation to the laws of nature, focusing on how properties determine temporal development, the causal roles of dispositions, and the necessary connection between dispositions and their manifestations. It discusses Humean metaphysics, the Humean best system for describing the distribution of matter throughout space-time, and the Super-Humeanism approach. The lecture also compares Humeanism with objective modality in explaining the patterns in fundamental physics and addresses the challenges in defining the primitive ontology and dynamical structure of theories.