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This lecture introduces the concept of diffusion in materials science, focusing on the movement of atoms and molecules under the influence of temperature. Topics include atomic vibrations, diffusion mechanisms, and their role in alloy solidification, semiconductor doping, nanowire growth, and material strengthening. The instructor explains how diffusion affects the evolution of materials over time, using examples such as interstitial and substitutional diffusion. Various diffusion processes, including homogenization and modification of microstructures, are discussed, highlighting the importance of understanding diffusion coefficients and laws. Practical applications like surface treatments and enhancing material properties through diffusion are also explored.