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This lecture introduces the concept of Generation IV (Gen IV) nuclear reactors, focusing on fast-spectrum reactors. It covers the sustainability of fast reactors, the breeding of fissile fuel, the properties of good coolants, and the historical development of fast reactors. The lecture discusses the advantages and disadvantages of different types of fast reactors, such as sodium-cooled, lead-cooled, and molten salt reactors. It also addresses key challenges in designing and operating molten salt reactors, emphasizing safety and sustainability. Overall, the lecture provides insights into the next generation of nuclear reactors and their potential to offer safe, sustainable, and efficient energy solutions.