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This lecture covers the histological structure and function of the epididymis, focusing on the different cell types present, such as smooth muscle cells, principal cells, and basal cells. It explains the role of stereocilia in absorption and secretion processes, the unique epithelial lining of the efferent ductules, and the structural changes along the epididymal duct. Additionally, it discusses the secretion of various substances by principal cells, the presence of intraepithelial lymphocytes, and the androgen-dependence of the epididymal epithelium.